Index
2022
2021
2020
2019
2018
2017
2012-2016
2011-2009
2008-2005
Before 2005

2004
 
Yan, B.* New combichem QC standards guards the supply of compounds and ensure HTS results,¡± Modern Drug Discovery. Feburary issue, 2004, 30-34.
 
Irving M, Krueger CA, Wade JV, Hodges JC, Leopold K, Chan C, Shaqair S, Shornikov A, Stock M, Collins N, Yan B. High-Throughput Purification of Combinatorial Libraries II: Automated Separation of Single Diastereomers from a 1920-Member 4-Amidopyrrolidinone Library. J Combi Chem 6, 478-486, 2004.
 
Jiang Zhao, Lu Zhang, Bing Yan, Strategies and Methods for Purifying Organic Compounds and Combinatorial Libraries. In Yan, B. Editor (2004) ¡°Analytical and purification methods in combinatorial chemistry¡± by John Wiley and Sons, New York.
 
The application of single bead FTIR and color test for reaction monitoring and building block validation in combinatorial library synthesis. Jason J. Cournoyer, Clinton A. Krueger, Janice V. Wade, Bing Yan, In Yan, B. Editor. ¡°Analytical and purification methods in combinatorial chemistry¡± by John Wiley and Sons, New York, 2004.
 
Yan B, Collins N, Wheatley J, Irving M, Leopold K, Chan C, Shornikov A, Fang L, Lee A, Stock M, Zhao J. High-Throughput Purification of Combinatorial Libraries I: A High-Throughput Purification System Using an Accelerated Retention Window Approach. J Combi Chem 6, 255-261, 2004.
 
2003
 
Fang L, Zhao J, Yan B. High throughput parallel LC/UV/MS analysis of combinatorial libraries in Methods in Enzymology Volume 369, Pages 3-21. Combinatorial Chemistry, Part B. Edited by: Guillermo A. Morales and Barry A. Bunin, 2003.
 
Yan B, Tang Q. Comparison of kinetics of organic reactions carried out on resin beads of different diameters. Industrial and Eng Chem Res 42 (24) 5964-5967, 2003.
 
Yan B. Editor. Chemical Analysis ¨C A Series of Monographs on Analytical Chemistry and Its Applications Volume 163 ¡°Analytical and purification methods in Combinatorial Chemistry¡± by John Wiley and Sons, Inc. 2003.Highlighted by: Journal of Natural Products, 2004, Vol. 67, No. 6, 1076.
Angew. Chem. Int. Ed. 2004, 43, 4552 ¨C 4553.
Drug Development And Industrial Pharmacy, 2004, Vol. 30, No. 7, p. 793.
 
Yan B, Fang L, Irving M, Zhang S, Boldi AM, Woolard F, Johnson CR, Kshirsagar T, Figliozzi GM, Krueger CA, Collins N. Quality Control in Combinatorial Chemistry: Determination of the Quantity, Purity, and Quantitative Purity of Compounds in Combinatorial Libraries. J Combi Chem 5(5), 547-559, 2003.
Highlighted by Faculty of 1000 Chemistry.
MODERN DRUG DISCOVERY SEPTEMBER issue, 2003, 11.
 
Fang L, Demee M, Cournoyer J, Sierra T, Young C, Yan B. Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray LC/UV/TOFMS system. Rapid Commun Mass Spectr 17, 1425-1432, 2003.
 
Yan B. Monitoring and Optimizing Organic Reactions Carried Out on Solid Support. Chapter in book Polymeric Materials in Organic Synthesis and Catalysis. Buchmeiser, M. R. Ed. Wiley-VCH, 2003.
 
2002
 
Yan B, Fang L, Irving M, Zhao J, Liu D, Figliozzi G, Woolard F, Krueger C. Analytical Methods for Optimization and Quality Control of Combinatorial Synthesis, chapter in Methods in Molecular Biology, Volume 201: Combinatorial Library Methods and Protocols, English, Lisa B. Ed. By Humana Press, 2002.
 
Fang L, Demee M, Sierra T, Zhao J, Tokushige D, Yan B. Optimization of an Eight-Channel Multiplexed Electrospray Time-of-Flight Mass Spectrometry (MUX-LCT) System for Combinatorial Library Analysis. Rapid Commun Mass Spectr 16, 1440-1447, 2002.
 
Yan B. Single bead analysis in combinatorial chemistry. Current Opinion in Chemical Biology 6, 328-332, 2002.
 
Fang L, Demee M, Sierra T, Kshirsagar T, Celebi A, Yan B. Kinetic Study of Amine Cleavage Reactions of Various Resin-Bound Thiophenol Esters from Marshall Linker. J Combi Chem 4, 362-368, 2002.
 
Cournoyer JJ, Kshirsagar T, Fantauzzi PP, Figliozzi GM, Makdessian T, Yan B. A Color Test for the Detection of Resin-Bound Aldehyde in Solid-Phase Combinatorial Synthesis. J Combi Chem 4, 120-124, 2002.
 
Yan, B., Fang, L., Irving, M., Zhao, J., Liu, D., Figliozzi, G., Woolard, F., Krueger. C.  Analytical Methods for Optimization and Quality Control of Combinatorial Synthesis, Methods in Molecular Biology, Volume 201: 189-200, ¡°Combinatorial Library Methods and Protocols¡±, English, Lisa B. Ed. By Humana Press, 2002.
 
Yan, B.*, Fang, L. Zhao, J. Irving, M. M. ¡°Analytical Techniques Applied in the Combinatorial Synthesis of Large Drug Discovery Libraries,¡± Analytical Sciences, 487i-490i, 2002.
 
2001
 
Irving MM, Kshirsagar T, Figliozzi GM, Yan B. Repeated Use of Solid Supports in Combinatorial Synthesis ¨C The Case of Marshall Resin Recycling. J Combi Chem 3, 407-409, 2001.
 
Fang L, Pan J, Yan B. High-throughput determination of identity, purity and quantity of combinatorial library members using LC/MS/UV/ELSD. Bioeng Biotech (Combi Chem) 71, 162-171, 2001.
 
Yan, B., Kshiragar, T., Fang, L., Fantauzzi, P., Pan, J. Analytical Methods in Library Feasibility and Rehearsal Studies. In Yan, B. and Czarnik, A. Editors (2001) ¡°Optimization of solid-phase combinatorial synthesis¡± by Marcel Dekker, New York.
 
 
Yan B, Czarnik A. Editors Optimization of solid-phase combinatorial synthesis by Marcel Dekker, New York, 2001.Highlighted by J. Am. Chem. Soc. 9 Vol. 124, No. 26, 2002 7875
 
Irving M, Cournoyer J, Li R, Santos C, Yan B. Qualitative and Quantitative Analyses of Resin-Bound Organic Compounds. Combinatorial Chemistry and High-Throughput Screening 4, 353-362, 2001.
 
Yan B, Yan H. Combination of Single Bead FTIR and Chemometrics in Combinatorial Chemistry: Application of Multivariate Calibration Method in the Monitoring of Solid Phase Organic Synthesis. J Combi Chem 3, 78-84, 2001.
 
2000
 
Yan B, Nguyen N, Liu L, Holland G, Raju B. Kinetic Comparison of Trifluoroacetic Acid Cleavage Reactions of Resin-Bound Carbamates, Ureas, Secondary Amides, and Sulfonamides from Benzyl-, Benzhydryl-, and Indole-Based Linkers. J Comb Chem 2(1) 66-74, 2000.
 
Gremlich HU, Yan B. Editors. Biological FTIR and Raman Spectroscopy by Marcel Dekker, New York, 2000.
Highlighted by J. Am. Chem. Soc., Vol. 123, No. 42, 2001 10427
 
Yan, B.* FTIR in Combinatorial Chemistry. Chemistry (Chinese Chemical Society, Taipei) 2000, 58(1) 139-144.
 
Yan B. Analytical methods for combinatorial chemistry ¨C a practical approach. In Combinatorial Chemistry ¨C A Practical Approach by Oxford University Press, Edited by Hicham Fenniri, 2000.
 
Yan, B.. (2000) Application of single bead FTIR in the optimization of solid-phase combinatorial and parallel syntheses.    Pept. New Millennium, Proc. Am. Pept. Symp., 16th  411-413.
 
1999
 
Yan B. Vibrational spectroscopy for optimization of solid-phase organic synthesis. In Solid-Phase Organic Synthesis by John Wiley, Edited by Kevin Burgess, 1999.
 
Yan B, Gremlich H-U. The Role of FTIR Methods in the Rehearsal Phase of Combinatorial Chemistry. J Chromatography B 725, 91-102, 1999.
 
Marti, R. E.; Martin, M. S; Yan, B.; Jarosinski, M. (1999) Solid-phase synthesis via 5-oxazolidinones. Ring opening reactions with amines and reaction monitoring by single bead FT-IR microspectroscopy. Pept. Proc. Am. Pept. Symp.15th, 305-306.
 
Yan B, Liu L, Astor CA, Tang Q. Determination of the Absolute Amount of Resin-Bound Hydroxyl or Carboxyl Groups for the Optimization of Solid-Phase Combinatorial and Parallel Organic Synthesis. Anal Chem 71(20) 4564-4571, 1999.
 
Yan B. Analytical methods in combinatorial chemistry by CRC Press (now Taylor & Francis), 1999.
Highlighted by Journal of Medicinal Chemistry, 2001, Vol. 44, No. 20, 3334.
 
Yan B, Martin PC, Lee J. Single Bead Fluorescence Microspectroscopy: Detection of Self-Quenching in Fluorescence-Labeled Resin Beads. J Combin Chem 1, 78-81, 1999.
 
Yan B, Gremlich H-U, Moss S, Coppola GM, Sun Q, Liu L. A comparison of various FTIR and FT raman methods: applications in the reaction optimization stage of combinatorial chemistry. J Combi Chem 1, 46-54, 1999.
 
1998
 
Jackson JC, Vinluan CC, Dragland CJ, Sundararajan V, Yan B, Gounarides JS, Nirmala NR, Topiol S, Ramage P, Blume JE, Aicher TD, Bell PA, Mann WR. Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex: Identification of important amino acid residues. Biochem J 334, 703-711, 1998.
 
Yan B. Monitoring the progress and the yield of solid-phase organic reactions directly on resin supports. Acct Chem Res 31, 621-630, 1998.
 
Yan B, Jewell Jr CF, Myers SW. Quantitatively monitoring of solid-phase organic synthesis by combustion elemental analysis. Tetrahedron 54, 11755-11766, 1998.
 
Li W, Yan B. Effects of Polymer Supports on the Kinetics of Solid-Phase Organic Reactions: A Comparison of Polystyrene- and TentaGel-Based Resins. J Org Chem 63, 4092-4097, 1998.
 
Sun Q, Yan B. Single bead IR monitoring a novel benzimidazole synthesis. Bioorg Med Chem Lett 8, 361-364, 1998.
 
Yan B, Sun Q. Crucial factors regulating site-interactions in resin supports determined by single bead IR. J Org Chem 63, 55-58, 1998.
 
Yan B. Properties of solid supports and their effects on solid-phase organic synthesis. Combinatorial Chemistry and High-Throughput Screening 1, 215-229, 1998.
 
1997
 
Shapiro M, Lin M,  Yan B. Analytical Tools for Combinatorial Chemistry in (ACS Book) Combinatorial Chemistry: A Short Course, S. H. DeWitt and A. W. Czarnik, Editors, 1997.
 
Yan B, Li W. Rapid fluorescence determination of the absolute amount of aldehyde and ketone groups on resin supports. J Org Chem 62, 9354-9357, 1997.
 
Li W, Yan B. A direct comparison of the mixing efficiency in solid-phase organic synthesis by single bead IR and fluorescence spectroscopy. Tetrahedron Lett 38, 6485-6488, 1997.
 
Marti R, Yan B, Jarosinski M. Solid phase synthesis via 5-oxazolidinones. Ring opening reactions with amines and reaction monitoring by single bead FTIR microspectroscopy. J Org Chem 62, 5615-5618, 1997.
 
Lin SL, Yan B. Three dimentional model of sensory rhodopsin I reveals important restraints between the protein and the chromophore. Protein Engineering 10, 197-206, 1997.
 
Yan B, Spudich EN, Sheves M, Spudich JL. Complexation of the signal transducing protein HtrI to sensory rhodopsin I and its effect on thermodynamics of signaling state deactivation. J Phys Chem B 101, 109-113, 1997.
 
1996
 
Yan B, Gstach H. Monitoring of solid-phase heterocyclic chemistry by Single bead IR. Tetrahedron Lett 37, 8325-8328, 1996.
 
Yan B, Sun Q, Wareing JR, Jewell CF. Real-time Monitoring of the Catalytic Oxidation of Alcohols on Resin Supports by Single Bead FTIR Microspectroscopy. J Org Chem 61, 8765-8770, 1996.
 
Yan B, Kumaravel G. Probing solid-phase reactions by monitoring the IR bands of compounds on a single "flattened" resin bead. Tetrahedron 52, 843-848, 1996.
 
Yan B, Fell JB, Kumaravel G. Progression of organic reactions on resin supports monitored by single bead FTIR microspectroscopy. J Org Chem 61, 7467-7472, 1996.
Highlighted by CHEMTRACTS-ORGANIC CHEMISTRY 10:822-827, 1997.
 
1995
 
Yan B, Spudich JL, Mazur P, Vunnam S, Derguini F, Nakanishi K. Spectral tuning in bacteriorhodopsin in the absence of counterion and coplanarization effects. J Biol Chem 270, 29668-29670, 1995.
 
Yan B, Kumaravel G, Anjaria H, Wu A, Petter RC, Jewell CF, Wareing J. Infrared spectrum of a single resin bead for real-time monitoring of solid-phase reactions. J Org Chem 60, 5736-5738, 1995.
Selected as Bio-Rad Application Note in 1996.
Mann, W. R., Yan, B., Dragland, C. J. and Bell, P. A. ¡°Kinetics, circular dichroism, and fluorescence studies on heterologously expressed carnitine palmitoyltransferase II,¡± J. Enzyme Inhibition. 1995, 9, 303-308.
 
Yan B, Mann WR, Bell P. Substrate-induced conformational changes in carnitine acetyltransferase. Biochim Biophys Acta 1253, 175-180, 1995.
 
Before 1995
 
Yan B, Xie A, Nienhaus GU, Katsuta Y, Spudich JL. Steric constraints in the retinal binding pocket of sensory rhodopsin I. Biochemistry 32, 10224-10232, 1993.
 
Yan B, Cline S, Doolittle WF, Spudich JL. Transformation of a BOP-HOP-SOP-I-SOP-II- Halobacterium halobium mutant to BOP+: effects of bacteriorhodopsin photoactivation on cellular proton fluxes and swimming behavior. Photochem Photobiol 56, 553-561, 1992.
Yan, B., Cline, S., Doolittle, W. F. & Spudich, J. L. ¡°Transformation of a bop-hop-sop-i-sop-ii- h-halobium mutant to bop+ - effects of bacteriorhodopsin photoactivation on cellular proton fluxes and swimming behavior,¡± FASEB J. 6, A531. 1992.
 
Takahashi, T; Yan, B; Spudich, JL, Sensitivity increase in the photophobic response of halobacterium-halobium reconstituted with retinal analogs - a novel interpretation for the fluence-response relationship and a kinetic modeling, Joint Us / Japan Seminar On The Biophysical Chemistry Of Retinal Proteins, 56, 1119-1128, 1992.
 
Takahashi T, Yan B, Spudich JL. Sensitivity increase in the photophobic response of Halobacterium halobium reconstituted with retinal analogs: a novel interpretation for the fluence-response relationship and a kinetic modeling. Photochem Photobiol 56, 1119-1128, 1992.
 
Ratto GM, Robinson DW, B Yan, McNaughton PA. Development of the light response in neonatal mammalian rods. Nature 351, 654-657, 1991.
 
Yan, B., R. Johnson, E.N. Spudich, K. Nakanishi & J.L. Spudich, Photoactivation of sensory rhodopsin I (SR-I): Some differences from bacteriorhodopsin and similarities to rhodopsin. Biophys. J. 59, 555A, 1991.
 
Yan B, Nakanishi K, Spudich JL. Mechanism of activation of sensory rhodopsin I: evidence for a steric trigger. Proc Natl Acad Sci USA 88, 9412-9416, 1991.
 
Ratto, G.M., D.W. Robinson, B. Yan & P.A. McNaughton. ¡°In vitro studies on the mechanism underlying the low sensitivity of neonatal rat rods,¡± J. Physiol. 1991, 438, 205p.
 
Yan B, Spudich JL. Evidence that the repellent receptor form of sensory rhodopsin I is an attractant signaling state. Photochem Photobiol 54, 1023-1026, 1991.
 
Yan B, Takahashi T, Johnson R, Spudich JL. Identification of signaling states of a sensory receptor by modulation of lifetimes of stimulus-induced conformations: the case of sensory rhodopsin II. Biochemistry 30, 10686-10692, 1991.
 
Yan B, Takahashi T, McCain DA, Rao VJ, Nakanishi K, Spudich JL. Effects of modifications of the retinal b-ionone ring on archaebacterial sensory rhodopsin I. Biophys J 57, 477-483, 1990.
 
Yan B, Takahashi T, Johnson R, Derguini F, Nakanishi K, Spudich JL. All-trans/13-cis isomerization of retinal is required for phototaxis signaling by sensory rhodopsins in halobacterium halobium. Biophys J 57, 807-814, 1990.
 
Takahashi T, Yan B, Mazur P, Derguini F, Nakanishi K, Spudich JL. Color regulation in the archaebacterial phototaxis receptor phoborhodopsin (sensory rhodopsin II). Biochemistry 29, 8467-8474, 1990.
 
Takahashi T, Yan B, Rao B, Nakanishi K, Spudich JL. Retinal analogs reconstitutions of bacterial sensory rhodopsin I. Biophys J 55, 383, 1989.