Before 2005


Jiao PF, Zhou HY, Otto M, Mu QX, Li LW, Su GX, Zhang Y, Butch E, Snyder S, Jiang GB, Yan B.* Leading Neuroblastoma Cells to Die by Multiple Premeditated Attacks from a Multifunctionalized Nanoconstruct. J Am Chem Soc 2011, 133(35), 13918-13921.

Gao NN, Zhang Q, Mu QX, Bai YH, Li LW, Zhou HY, Butch E, Powell T, Snyder SE, Jiang GB, Yan B.* Steering Carbon Nanotubes to Scavenger Receptor Recognition by Nanotube Surface Chemistry Modification Partially Alleviates NF¦ÊB Activation and Reduces Its Immunotoxicity. ACS Nano 2011, 5(6), 4581-4591.

Li LW, Zhang Q, Liu AF, Li, XE, Zhou HY, Liu Y, Yan B.* Proteome Interrogation Using Nanoprobes to Identify Targets of a Cancer-killing Molecule. J Am Chem Soc 2011, 133(18), 6886-6889.

Zhou HY, Jiao PF, Yang L, Li X, Yan B.* Enhancing Cell Recognition by Scrutinizing Cell Surfaces with a Nanoparticle Array. J Am Chem Soc 2011, 133(4), 680-682.

Parkinson EI, Hatfield MJ, Hyatt JL, Hicks LD, Edwards CC, Yan B, Potter PM. Requirements for Mammalian Carboxylesterase Inhibition by Substituted Ethane-1,2-diones. Bioorg Med Chem 2011, 19(15), 4635-4643.

Yu C, Zhang J, Chen L*, Li J, Liu P, Wang W, Yan B.* ¡°Off-On¡± Based Fluorescent Chemosensor for Cu2+ in Aqueous Media and Living Cells. Talanta 2011, 85(3), 1627-1633.

Liu YJ, Zhang B, Yan B.* Enabling Anticancer Therapeutics by Nanoparticle Carriers: The Delivery of Paclitaxel. Int J Mol Sci 2011, 12(7), 4395-4413.

Andersson AK, Miller DW, Lynch J, Lemoff AS, Cai Z, Pounds SB, Radtke I, Yan B, Schuetz JD, Rubnitz JE, Ribeiro RC, Raimondi SC, Zhang J, Mullighan CG, Shurtleff SA, Schulman BA, Downing JR. IDH1 and IDH2 Mutations in Pediatric Acute Leukemia.Leukemia, Web Publication Date: June 7, 2011.

Hurdle JG, Heathcott AE, Yang L, Yan B, Lee RE. Reutericyclin and Related Analogues Kill Stationary Phase Clostridium Difficile at Achievable Colonic Concentrations. J Antimicrob Chemother 2011, 66(8), 1773-1776.

Tekobo S, Richter AG, Dergunov SA, Pingali SV, Urban VS, Yan B, Pinkhassik E. Synthesis, Characterization, and Controlled Aggregation of Biotemplated Organic Nanodisks. J Nanoparticle Research, Web Publication Date: May 11, 2011.

Zhou QF, Dergunov SA, Zhang Y, Li X, Mu QX, Zhang Q, Jiang GB, Pinkhassik F, Yan B.* Safety profile and cellular uptake of biotemplated nanocapsules with nanometer-thin walls. Nanoscale 2011, 136, 872-877.

Wu L and Yan B.* Discovery of Small Molecules that Target Autophagy for Cancer Treatment. Current Medicinal Chemistry 2011, 18(12), 1866-1873 (One of the 10 most accessed papers in the first month of publication).

Yan B. Impacts of Nanotechnology on Medicinal Chemistry and Drug Discovery. Current Medicinal Chemistry 2011, 18(14), 2044.

Jiao P, Zhou H, Chen L, Yan B.* Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy. Current Medicinal Chemistry 2011, 18(14), 2086-2102 (One of the 10 most accessed papers in the first month of publication).

Yan B, Editorial: Nano-Combinatorial Chemistry and Associated Technologies,Combinatorial Chemistry & High Throughput Screening 2011, 14(3), 146.

Zhang W, Penmatsar H, Ren A, Punchihewa C, Lemoff A, Yan B, Fujii N and Naren AP. Functional Regulation of CFTR-Containing Macromolecular Complexes: A Small-Molecule Inhibitor Approach. Biochemical Journal 2011, 435, 451¨C462 (Highlighted by Commentary "Targeting the regulation of CFTR channels" by Paul DWE and Christine EB, Biochem J 2011, 435, e1¨Ce4).

Liu Y, Yan B.* Characterizing the Surface Chemistry of Nanoparticles: An Analogy to Solid-Phase Synthesis Samples. Combinatorial Chemistry & High Throughput Screening 2011, 14(3), 191-197.

Li X, Zhou HY, Yang L, Du GQ, Pai-Panandiker A, Huang XF, and Yan B.* Enhancement of Cell Recognition in vitro by Dual-Ligand Cancer Targeting Gold Naoparticles.Biomaterials 2011, 232, 2540-2545.

Gasser M, Rothen-Rutishauser B, Krug HF, Gehr P, Nelle M, Yan B and Wick P. The Adsorption of Biomolecules to Multi-Walled Carbon Nanotubes is Influenced by Both Pulmonary Surfactant Lipids and Surface Chemistry. Journal of Nanobiotechnology2010, 8:31.

Liu YY, Su GX, Zhang B, Jiang GB, Yan B.* Nanoparticle-Based Strategies for Detection and Remediation of Environmental Pollutants. Analyst 2011, 136(5), 872-877 (Designated by Royal Society of Chemistry as one of the top five most-read articles from the online version of Analyst for February 2011).

Wang GQ, Chen ZP, Wang WH, Yan B and Chen LX. Chemical Redox-Regulated Mesoporous Silica-Coated Gold Nanorods for Colorimetric Probing of Hg2+ and S2-.Analyst, 2011, 136(1), 174-178.

Wang F, Zhai SM, Liu XJ, Li LW, Wu S, Dou QP* and Yan B.* A Novel Dithiocarbamate Analogue with Potentially Decreased ALDH Inhibition has Copper-Dependent Proteasome-Inhibitory and Apoptosis¨CInducing Activity in Human Breast Cancer Cells.Cancer Letters 2011, 300(1), 87-95.


Bai YH, Zhang Y, Zhang JP, Mu QX, Zhang WD, Butch ER, Snyder SE, Yan B.* Repeated Carbon Nanotube Administrations in Male Mice Cause Reversible Testis Damage without Affecting Fertility. Nature Nanotechnology 2010, 5(9), 683-689 ----Highlighted by (1) RSC Chemistry World, Nanowerk, Institute of Nanotechnology, Meridian Institute and Softpedia; (2) Nature China, September 1, 2010; (3) Beijing Ke Ji Bao, October 11, 2010.

Luo M and Yan B.* Enantioselective Henry Reactions Catalyzed by Chiral N-Metal Complexes Containing R(+)/ S(-)-<alpha>-Ethylphenyl Amines. Tetrahedron Letters 2010, 51(42), 5577-5580.

Yan B, Zhang B. Analytical Methods in Combinatorial Chemistry, Second Edition, CRC Press, Taylor & Francis Group. ISBN: 978-0-8493-1860-3. Publication date: August 9, 2010.

Mahindroo N, Connelly MC, Punchihewa C, Yang L, Yan B and Fujii N. Amide Conjugates of Ketoprofen and Indole as Inhibitors of Gli1-Mediated Transcription in the Hedgehog Pathway. Bioorganic Medicinal Chemistry 2010, 18(13), 4801-4811.

Su, G.X., Yan, B.* Nano-Combinatorial Chemistry Strategy for Nanotechnology Research. J. Combi. Chem. 2010, 12(2), 215-221.

Zhang Y, Bai Y, Yan B.* Functionalized Carbon Nanotubes for Potential Medicinal Applicatons. Drug Discovery Today 2010, 15(11-12), 428-435.

Liu W, Wu Y, Wang C, Li HC, Wang T, Liao CY, Cui L, Zhou QF, Yan B & Jiang GB. Impact of Silver Nanoparticles on Human Cells: Effect of Particle Size. Nanotoxicology 2010, 4(3), 319-330.

Li LW, Mu QX, Zhang B, Yan B.* Analatical Strategies for Detection Nanoparticles-Protein Interaction. Analyst 2010, 135(7), 1519-1530 (Designated by Royal Society of Chemistry as one of the most-read articles from the online version of Analyst for the first month of publication).

Zhou HY, Li X, Lemoff A, Zhang B, Yan B.* Structural Confirmation and Quantification of Individual Ligands from the Surface of Multi-Functionalized Gold Nanoparticles. Analyst 2010, 135(6), 1210-1213.

Mu QX, Yang L, Davis JC, Vankayala R, Hwang KC, Zhao JC, Yan B.* Biocompatibility of Polymer Grafted Core/Shell Iron/Carbon Nanoparticles. Biomaterials 2010, 31(19), 5083-5090.

Tu Y, Jeffries C, Ruan H, Nelson C, Smithson D, Shelat AA, Brown KM, Li X-C, Hester JP, Smillie T, Khan IA, Walker L, Guy K*, Yan B.* An Automated High-Throughput System to Fractionate Natural Products for Drug Discovery. J Nat Prod 2010, 73(4), 751-754 (Rated #1 most read research article by ACS in the first four months of publication).

Zhang, Q, Zhou, H, Zhai, S, Yan, B.* Natural Product-Inspired Synthesis of Thiazolidine and Thiazolidinone Compounds and Their Anticancer Activities. Current Pharmaceutical Design 2010, 16(16), 1826-1842.

Wang, F, Jiao, P, Qi, M, Frezza, M, Dou, Q*, Yan, B.* Turning Tumor-Promoting Copper into an Anti-Cancer Weapon via High-Throughput Chemistry. Current medicinal Chemistry 2010, 17(25), 2685-2698.

Zhai, S, Yang, L, Cui, Q, Sun, Y, Dou, Q*, Yan, B.* Tumor Cellular Proteasome Inhibition and Growth Suppression by 8-Hydroxylquinoline and Clioquinol Requires Their Capabilities to Bind Copper and Transport Copper into Cells. J Biological Inorganic Chemistry 15(2), 259-269, 2010.

Zhou, H, Zhang, W, Yan, B.* Use Cyclohexylcyanide and Methyl 2-Isocyanoacetate as Convertibel Isocyanides for Microwave-Assisted Fluorous Synthesis of 1,4-Benzodiazepine-2,5-dione Library. J Comb Chem 12(1), 206-214, 2010.

Zhang B, Yan B.* Analytical Strategies for Characterizing Nanoparticle s Surface Chemistry. Anal Bioanal Chem 396(3), 973-982, 2010.

Qiu Zhang, Hongyu Zhou, Bing Yan. Reducing nanotube cytotoxicity using nano-combinatorial library approach, chapter in K. Balasubramanian and M. Burghard, eds. Methods in Molecular Biology Series on Carbon Nanotubes, Humana Press, Inc. NJ, U.S.A., 95-108, 2010.

Qingxin Mu, Shumei Zhai, Bing Yan. Real-time Monitoring of Cellular Responses to Carbon Nanotubes, chapter in K. Balasubramanian and M. Burghard, eds. Methods in Molecular Biology Series on Carbon Nanotubes, Humana Press, Inc. NJ, U.S.A., 85-94, 2010


Mu, Q, Broughton, D, Yan, B.* Endosomal Leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake. Nano Letters 9(12), 2009,4370-4375.

Wu, Z, Zhang, B, Yan, B.* Regulation of Enzyme Activity through Interactions with Nanoparticles. International Journal of Molecular Sciences 10(10), 4198-4209, 2009.

Liu, A, Zhou, H, Su, G, Zhang, W, Yan, B.* Fluorous Synthesis of 1,4-Benzodiazepine-2,5-dione Library. J Comb Chem 11(6), 1083-1093, 2009.

Yan, B. and Czarnik, AW, Book Series Editors, Critical Review in Combinatorial Chemistry Volume 5. Chen, T. Book ¡°High-Throughput Screening Technologies¡± by Francis and Taylor Group, 2009.

Milacic, V, Jiao, PF, Zhang, B, Yan, B*, Dou, QP.* Novel 8-Hydroxylquinoline Analogs Induce Copper-Dependent Proteasome Inhibition and Cell Death in Human Breat Cancer Cells.International Journal of Oncology,35(6), 1481-1491, 2009.

Luo, M*, Yan, B.*A Simple Synthesis of Octaphenylcyclotetra(Siloxane). Tetrahedron Letters 50(37), 5208-5209, 2009.

Mu, QX, Du, GQ, Chen, TS, Zhang, B, Yan, B.* Suppression of Human Bone Mophorgenetic Protein (BMP) Signaling by Carboxylated Single-Walled Carbon Nanotubes. ACS Nano,3(5), 1139-1144, 2009.

Zhang, B, Xing, YH, Zhou, HY, Li, ZW, Mu, QX, Yan, B.* Functionalized Carbon Nanotubes Specifically Bind to Chymotrypsin Catalytic Site and Regulate its Enzymatic Function. Nano Letters,9(6), 2280-2284, 2009.

Zhang, Q, Feng, W, Zhou, HY, Yan, B.* Advances in Preclinical Small Molecules for the Treatment of Non-Small Cell Lung Cancer. Expert Opinion on Therapeutic Patents,19(6), 731-751, 2009.

Qu, G, Bai, Y, Zhang, Y, Jia, Q, Zhang, W, Yan, B*. The effect of multiwalled carbon nanotube agglomeration on their accumulation in and damage to organs in mice. Carbon,47, 2060-2069, 2009.

Mu, Q, Li, Z, Li, X, Mishra, SR, Zhang, B, Si, Z, Yang, L, Jiang, W, Yan, B*. Characterization of Protein Clusters of Diverse Magnetic Nanoparticles and Their Dynamic Interactions with Human Cells. J Phys Chem C 113 (14), 5390¨C5395, 2009.

Ma, XF, Shi, RR, Zhang, B, Yan, B.* Kinetics of Resin-Supported Mitsunobu Esterification and Etherification Reactions. J Comb Chem 11 (3) 438-445, 2009.

Du, FF, Zhou, HY, Chen, LX, Zhang, B, Yan, B*. Structure Elucidation of Nanoparticle-Bound Organic Molecules By 1H NMR. Trends in Analytical Chemistry 28(1), 88-95, 2009.